Teneligliptin is a DPP-4 inhibitor, which is believed to exert its actions in patients with type 2 diabetes by slowing the inactivation of Incretin hormones. Concentrations of the active intact hormones are increased by Teneligliptin, thereby increasing and prolonging the action of these hormones.Ingredients:Each film coated tablet contains: Teneligliptin Hydrobromide Hydrate equivalent to Teneligliptin 20 mgBenefits:Type 2 diabetes mellitus: The drug product should be used only in patients who have not sufficiently responded to either of the following treatments. (a) Diet and/or exercise therapy alone (b) Use of sulfonylureas in addition to diet and/or exercise therapy (c) Use of thiazolidinedione’s in addition to diet and/or exercise therapyHow to use:The usual adult dosage is 20 mg of Teneligliptin administered orally once daily. If efficacy is insufficient, the dose may be increased up to 40 mg once daily while closely monitoring the clinical course.Precautions:Teneligliptin is contraindicated in the following: • Any patient with a known hypersensitivity to Teneligliptin or any of the components in the formulation, • Severe ketosis, diabetic coma or history of diabetic coma, type 1 diabetic patients, • Patients with severe infection, surgery, severe trauma (blood sugar control should preferably be done by insulin).
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